UCM
Research/art/teacher profile of a person
Name and surname:
 doc. Ing. Tibor Maliar, PhD.
Email:
 tibor.maliar@ucm.sk
Homepage:
 http:\\
Fakulta/Univerzita:
FPV UCM - Faculty of Natural Sciences
Pracovisko:
UCHEV - Ústav chémie a environmentálných vied

I. - Basic information

I.1 - Surname
Maliar
I.2 - Name
Tibor
I.3 - Degrees
assoc. prof. Ing. PhD.
I.4 - Year of birth
1966
I.5 - Name of the workplace
Department of Chemistry and Environmental Sciences FNS UCM in Trnava
I.6 - Address of the workplace
Námestie Jozefa Herdu 2. Trnava, 917 01, Hlavná 418, Špačince, 919 51
I.7 - Position
associate professor
I.8 - E-mail address
tibor.maliar@ucm.sk
I.9 - Hyperlink to the entry of a person in the Register of university staff
https://www.portalvs.sk/regzam/detail/14372
I.10 - Name of the study field in which a person works at the university
17. Chemistry
I.11 - ORCID iD
0000-0003-2894-636X

II. - Higher education and further qualification growth

II.1 - First degree of higher education
II.a - Name of the university or institution
STU Bratislava
II.b - Year
1989
II.c - Study field and programme
Fermentation chemistry and bioengineering
II.2 - Second degree of higher education
II.a - Name of the university or institution
STU Bratislava
II.b - Year
1989
II.c - Study field and programme
Fermentation chemistry and bioengineering
II.3 - Third degree of higher education
II.a - Name of the university or institution
STU Bratislava
II.b - Year
2005
II.c - Study field and programme
Biotechnology
II.4 - Associate professor
II.a - Name of the university or institution
STU Bratislava
II.b - Year
2017
II.c - Study field and programme
Biochemistry
II.5 - Professor
II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position III.b - Institution III.c - Duration
University teacher, scientist, project manager FNS, UCM in Trnava 2001- up to now
scientist, projects leader DRIM, Inc. Modra 1989-2005
Faculty project manager FNS UCM in Trnava 2005 -2007, 2018 - 2021
researcher, project leader FRI Bratislava, Biocentre Modra 2007 - 2009

IV. - Development of pedagogical, professional, language, digital and other skills

IV.a - Activity description, course name, other IV.b - Name of the institution IV.c - Year
International certificate on CADD ICS - UNIDO 2000
Good laboratory praxis ŠUKL 1991

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes
V.1.a - Name of the profile course V.1.b - Study programme V.1.c - Degree V.1.d - Field of study
Basic medicinal chemistry Chemistry I Chemistry
Basic pharmaceutical chemistry Chemistry I. Chemistry
Advanced medicinal chemistry Applied chemistry II. Chemistry
Computer molecule design Applied chemistry II. Chemsitry
Biochemistry Chemistry I. Chemistry
V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year
V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year
V.4 - Overview of supervised final theses
V.4.1 - Number of currently supervised theses
V.4.a - Bachelor's (first degree)
0
V.4.b - Diploma (second degree)
2
V.4.c - Dissertation (third degree)
2
V.4.2 - Number of defended theses
V.4.a - Bachelor's (first degree)
17
V.4.b - Diploma (second degree)
18
V.4.c - Dissertation (third degree)
2
V.5 - Overview of other courses taught in the current academic year according to study programmes
V.5.a - Name of the course V.5.b - Study programme V.5.c - Degree V.5.d - Field of study
The work with chenical literature Chemistry I. Chemistry
Basic user software Chemistry I. Chemistry

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations
VI.1.1 - Number of the research/artistic/other outputs
VI.1.a - Overall
80
VI.1.b - Over the last six years
20
VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases
VI.1.a - Overall
42
VI.1.b - Over the last six years
10
VI.1.3 - Number of citations corresponding to the research/artistic/other outputs
VI.1.a - Overall
556
VI.1.b - Over the last six years
82
VI.1.4 - Number of citations registered in the Web of Science or Scopus databases
VI.1.a - Overall
556
VI.1.b - Over the last six years
82
VI.1.5 - Number of invited lectures at the international, national level
VI.1.a - Overall
3
VI.1.b - Over the last six years
1
VI.2 - The most significant research/artistic/other outputs

MALIAR T.(25%), JEDINÁK A., KADRABOVÁ J., ŠTURDÍK E. Structural aspects of flavonoids as trypsin inhibitors, Eur. J. Med. Chem. 39: 241-248, 2004, 82 cit.

JEDINAK A., MALIAR T.(25%), GRANCAI D., NAGY M. Inhibition activities of natural products on serine proteases. Phytother. res. 20 (3): 214-217, 2006, 62 cit.

JEDINAK A, MUCKOVA M, KOST'ALOVA D, MALIAR T., MASTEROVA I. Antiprotease and antimetastatic activity of ursolic acid isolated from Salvia officinalis. Z Naturforsch [C], 61(11-12): 777-782, 2006,59 cit.

JEDINAK A., MALIAR T(50%). Inhibitors of proteases as anticancer drugs. Neoplasma, 2(3):185-92, 2005, 47 cit.

TOSSII A., BONIN I., ANTCHEVA N., NORBEDO S., BENEDETTI F., MIERTUŠ S., NAIR C. A., MALIAR T.(10%), DAL BELLO F., PALU G., ROMEO D. Aspartic proteinase inhibitors: An integrated approach for the design and synthesis of diaminodiol based peptidomimetics, Eur. J. Biochem. 267: 1715-1722, 2000, 39 cit.

VI.3 - The most significant research/artistic/other outputs over the last six years

Kulichová, K., Sokol, J., Nemeček, P., Maliarová, M., Maliar, T.(10%), Havrlentová, M., Kraic, J.: Phenolic compounds and biological activities of rye (Secale cereale L.) grains. Open Chemistry, 17(1): 988 – 999, 2019, 39 cit.

Koreň, J., Andrezál, M., Drahovská, H., Hubenáková, Z., Liptáková, A., Maliar, T.(8%): Next-Generation Sequencing of Carbapenem-Resistant Klebsiella pneumoniae Strains Isolated from Patients hospitalized in the University Hospital Facilities. Antibiotics, 11(11): 1538, 2022, 8 cit.

Maliar, T.(15%); Maliarová, M.; Purdešová, A.; Jankech, T.; Gerhardtová, I.; Beňovič, P.; Dvořáček, V.; Jágr, M.; Viskupičová, J. The Adapted POM Analysis of Avenanthramides In Silico. Pharmaceuticals, , 16(5): 717, 2023, 8 cit.

Ürgeová, E.; Uváčková, Ľ.; Vaneková, M.; Maliar, T (20%). Antibacterial Potential of Microwave-Assisted Extraction Prepared Hydrolates from Different Salvia Species, Plants, 12(6): 1325, 2023, 6 cit.

Vulganová, K.; Maliar, T.; Maliarová, M.; Nemeček, P.; Viskupičová, J.; Balážová, A.; Sokol, J. Biologically valuable components, antioxidant activity and proteinase inhibition activity of leaf and callus extracts of Salvia sp.Nova Biotechnologica et Chimica, 18(1): 25–36, 2019, 3 citácie.

VI.4 - The most significant citations corresponding to the research/artistic/other outputs

MALIAR T., JEDINÁK A., KADRABOVÁ J., ŠTURDÍK E. Structural aspects of flavonoids as trypsin inhibitors, Eur. J. Med. Chem. 39: 241-248, 2004, 82 citations.

  1. Probing the binding mechanisms of alpha-tocopherol to trypsin and pepsin using isothermal titration calorimetry, spectroscopic, and molecular modeling methods. By: Li, Xiangrong; Ni, Tianjun. JOURNAL OF BIOLOGICAL PHYSICS Volume: 42 Issue: 3 Pages: 415-434 Published: JUN 2016.
  2. Study on the interaction of -carotene and astaxanthin with trypsin and pepsin by spectroscopic techniques. By: Li, Xiangrong; Li, Peihong. LUMINESCENCE Volume: 31 Issue: 3 Pages: 782-792 Published: MAY 2016.
  3. Probing the binding of procyanidin B3 to trypsin and pepsin: A multi-technique approach. By: Li, Xiangrong; Geng, Mingjiang. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES Volume: 85 Pages: 168-178 Published: APR 2016.
  4. Morin: A Promising Natural Drug. By: Caselli, Anna; Cirri, Paolo; Santi, Alice; et al. CURRENT MEDICINAL CHEMISTRY Volume: 23 Issue: 8 Pages: 774-791 Published: 2016.
  5. Inhibitory effect of a quercetin-based soaking formulation and modified atmospheric packaging (MAP) on muscle degradation of Pacific white shrimp (Litopenaeus vannamei). By: Qian, Yun-Fang; Xie, Jing; Yang, Sheng-Ping; et al. LWT-FOOD SCIENCE AND TECHNOLOGY Volume: 63 Issue: 2 Pages: 1339-1346 Published: OCT 2015.

TOSSII A., BONIN I., ANTCHEVA N., NORBEDO S., BENEDETTI F., MIERTUŠ S., NAIR C. A., MALIAR T., DAL BELLO F., PALU G., ROMEO D. Aspartic proteinase inhibitors: An integrated approach for the design and synthesis of diaminodiol based peptidomimetics, Eur. J. Biochem. 267: 1715-1722, 2000, 39 citations.

  1. Inhibitors of HIV-Protease from Computational Design. A History of Theory and Synthesis Still to be Fully Appreciated. By: Berti, Federico; Frecer, Vladimir; Miertus, Stanislav. CURRENT PHARMACEUTICAL DESIGN Volume: 20 Issue: 21 Pages: 3398-3411 Published: 2014.
  2. Aspartic Peptidases of Human Pathogenic Trypanosomatids: Perspectives and Trends for Chemotherapy. By: Santos, L. O.; Garcia-Gomes, A. S.; Catanho, M.; et al. CURRENT MEDICINAL CHEMISTRY Volume: 20 Issue: 25 Pages: 3116-3133 Published: AUG 2013.
  3. Design of Novel Dihydroxynaphthoic Acid Inhibitors of Plasmodium Falciparum Lactate Dehydrogenase. By: Megnassan, Eugene; Keita, Melalie; Bieri, Cecile; et al. MEDICINAL CHEMISTRY Volume: 8 Issue: 5 Pages: 970-984 Published: SEP 2012.
  4. Design, Synthesis and Evaluation of Unique 2,4,5-triaryl Imidazole Derivatives as Novel Potent Aspartic Protease Inhibitors. By: Khan, Mohd Sajid; Akhtar, Salman; Siddiqui, S. A.; et al. MEDICINAL CHEMISTRY Volume: 8 Issue: 3 Pages: 428-435 Published: MAY 2012.
  5. Synthesis and Biological Activity of Potent HIV-1 Protease Inhibitors Based on Phe-Pro Dihydroxyethylene Isosteres. Benedetti Fabio; Berti Federico; Budal Sara; et al. JOURNAL OF MEDICINAL CHEMISTRY Volume: 55 Issue: 8 Pages: 3900-391. 2012.

JEDINAK A., MALIAR T., GRANCAI D., NAGY M. Inhibition activities of natural products on serine proteases. Phytother. res. 20 (3): 214-217, 2006, 62 citations.

  1. 1. Popular naturally ocurring antioxidants as potential anticoagulant drugs. By: Bijak, Michal; Saluk, Joanna; Szelenberger, Rafal; et al. CHEMICO-BIOLOGICAL INTERACTIONS Volume: 257 Pages: 35-45 Published: SEP 25 2016.
  2. Enzyme Inhibitory and Molecular Docking Studies on Some Organic Molecules of Natural Occurrence. By: Abbasi, Muhammad Athar; Hussain, Ghulam; Aziz-ur-Rehman; et al. JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN Volume: 38 Issue: 1 Pages: 166-170 Published: FEB 2016.
  3. Colloidal Aggregation and the in Vitro Activity of Traditional Chinese Medicines. By: Duan, Da; Doak, Allison K.; Nedyalkova, Lyudmila; et al. ACS CHEMICAL BIOLOGY Volume: 10 Issue: 4 Pages: 978-988 Published: APR 2015.
  4. Evaluation of the Therapeutic Potential of Cefradine Metal Complexes. By: Danish, Muhammad; Raza, Muhammad A.; Sharif, Amina; et al. LATIN AMERICAN JOURNAL OF PHARMACY Volume: 34 Issue: 6 Pages: 1167-1171 Published: 2015.
  5. Radical Scavenging, Proteases Activities, and Phenolics Composition of Bark Extracts from 21 Medicinal Plants. By: Raza, Muhammad Asam; Shahwar, Durre; Khan, Tania. JOURNAL OF CHEMISTRY Article Number: 951840 Published: 2015.

JEDINAK A, MUCKOVA M, KOSTALOVA D, MALIAR T., MASTEROVA I. Antiprotease and antimetastatic activity of ursolic acid isolated from Salvia officinalis. Z Naturforsch [C], 61(11-12): 777-782, 2006, 59 citations.

  1. Ursolic acid (UA): A metabolite with promising therapeutic potential. By: Kashyap, Dharambir; Tuli, Hardeep Singh; Sharma, Anil K. LIFE SCIENCES Volume: 146 Pages: 201-213 Published: FEB 1 2016.
  2. Role of Isoprenoid Compounds on Angiogenic Regulation: Opportunities and Challenges. By: Guerra, Angela R.; Duarte, Iola F.; Duarte, Maria F. CURRENT MEDICINAL CHEMISTRY Volume: 23 Issue: 9 Pages: 911-928 Published: 2016.
  3. Bioactive Triterpenic Acids: From Agroforestry Biomass Residues to Promising Therapeutic Tools. By: Domingues, Rui M. A.; Guerra, Angela R.; Duarte, M.; et al. MINI-REVIEWS IN ORGANIC CHEMISTRY Volume: 11 Issue: 3 Pages: 382-399 Published: 2014.
  4. Chemotype Diversity of Indigenous Dalmatian Sage (Salvia officinalis L.) Populations in Montenegro. By: Stesevic, Danijela; Ristic, Mihailo; Nikolic, Vuko; et al. CHEMISTRY & BIODIVERSITY Volume: 11 Issue: 1 Pages: 101-114 Published: JAN 2014.
  5. Research progress of ursolic acid's anti-tumor actions. By: Zang Li-li; Wu Bao-ning; Lin Yuan; et al. CHINESE JOURNAL OF INTEGRATIVE MEDICINE Volume: 20 Issue: 1 Pages: 72-79 Published: JAN 2014.

JEDINAK A., MALIAR T. Inhibitors of proteases as anticancer drugs. Neoplasma, 2(3):185-92, 2005, 47 citations.

  1. Characterization, biomedical and agricultural applications of protease inhibitors: A review. By: Shamsi, Tooba Naz; Parveen, Romana; Fatima, Sadaf. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES Volume: 91 Pages: 1120-1133 Published: OCT 2016.
  2. Cathepsin S: therapeutic, diagnostic, and prognostic potential. By: Wilkinson, Richard D. A.; Williams, Rich; Scott, Christopher J.; et al. BIOLOGICAL CHEMISTRY Volume: 396 Issue: 8 Pages: 867-882 Published: AUG 2015.
  3. Acyl hydrazides and triazoles as novel inhibitors of mammalian cathepsin B and cathepsin H. By: Raghav, Neera; Singh, Mamta EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY Volume: 77 Pages: 231-242 Published: APR 2014.
  4. Anti-proliferative and metastatic protease inhibitory activities of protoberberines: An in silico and in vitro approaches. By: Kumari, Seema; Kaladhar, D. S. V. G. K.; Solmon, K. Sandeep; et al. PROCESS BIOCHEMISTRY Volume: 48 Issue: 10 Pages: 1565-1571 Published: OCT 2013.
  5. Silencing of Cathepsin B suppresses the proliferation and invasion of endometrial cancer. By: Bao, Wei; Fan, Qiong; Luo, Xin; et al. ONCOLOGY REPORTS Volume: 30 Issue: 2 Pages: 723-730 Published: AUG 2013
VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years

SRDA-16-0173: Therapeutic alternatives to therapy of resistant, bacterial infections. 2016 - 2021, 222 562 €. Project principal investigator.

SRDA-20-0413: The physical biomass processing as a source of bioactive compounds with antiviral, antibacterial and anti-inflammatory affect for another application. 2020 - 2023, 240 496 €. Projcet principal investigator.

VEGA-01/0660/18: The research of the efectors (inhibitors and activators) of carnosinase ((beta-alanyl-histidien dipeptidase), saimed to optimise a plasmatic and tissue carnosine level. 2018 - 2020, 20 000 €. Deputy of projcet principal investigator. Projcet principal investigator for UCM in Trnava.

SRDA -17- 0113. The elimination of avenin toxicity for healthy, safe and nontraditional food products, 2018- 2022, 200 253 €. The person responsible for part of the procets on UCm in Trnava.

NFP313010V344: Longtime, strategic reserach of the prevention, intervention about obesity mechanism and its comorbidities. 2019 - 2023, 7 166 370 €. Project principal investigator for UCM in Trnava.

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VII.a - Activity, position VII.b - Name of the institution, board VII.c - Duration
Person responsible for teaching profile subjects of study program Chemistry in the I.-st degree. FNS UCM in Trnava 2022-now
Person responsible for teaching profile subjects of study program Applied chemistry in the II.-nd degree. FNS UCM in Trnava 2022-now
FNS UCM in Trnava 2014-2018

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

VIII.a - Name of the institution VIII.b - Address of the institution VIII.c - Duration (indicate the duration of stay) VIII.d - Mobility scheme, employment contract, other (describe)
Polytech Area Science Park Terst, Italy 1998- 2000 ICS- INIDO membership
Univesity of Nigde Nigde, Italy 2014 ERASMUS

IX. - Other relevant facts

IX.a - If relevant, other activities related to higher education or research/artistic/other activities are mentioned

The cooperation with other universities and academic workplaces in Slovakia (STU BA, CU BA, SAU NR, SAS Bratislava) nad private, commercial organizations.

Date of last update
2025-03-11